Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALPL | P05186 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888912 | 0.78 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL1413959 | 0.76 | ALPL (1.00) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL2631731 | 0.75 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL1414008 | 0.75 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL14152359 | 0.71 | ALPL (1.00) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL2848443 | 0.70 | ALPL (0.76) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL28024007 | 0.69 | MAPT (0.48) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1413966 | 0.69 | ALPL (1.00) | MAPTNPC1RAB9AL3MBTL1ALPL | |
| SCHEMBL9050226 | 0.68 | RAB9A (0.84) | MAPTNPC1RAB9AALPLLMNA | |
| SCHEMBL13539283 | 0.68 | ALPL (0.73) | MAPTRAB9AALPLCA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104814956-A | Use of ethyl (S)-1-(3-p-chlorophenoxy-2-hydroxypropyl)-3-p-methoxyphenyl-1H-pyrazolyl-5-carboxylate in pharmacy | UNIV SHANDONG | 2015-08-05 | — | — | CN | disclosed |