Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | MARS1 | P56192 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677824 | 0.95 | MARS1 (0.46) | LMNAKMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL27677861 | 0.91 | CYP1A2 (0.46) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL28760197 | 0.91 | CYP1A2 (0.49) | LMNAKMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL8889722 | 0.72 | MAPT (0.70) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL8368086 | 0.71 | MAPT (0.61) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4716157 | 0.70 | GABRA1 (0.51) | MAPTLMNACYP2D6ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8370004 | 0.70 | MAPT (0.60) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14180952 | 0.70 | CNR1 (0.47) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL2730926 | 0.70 | PHGDH (0.59) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28024005 | 0.69 | MAPT (0.62) | MAPTLMNASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104814956-A | Use of ethyl (S)-1-(3-p-chlorophenoxy-2-hydroxypropyl)-3-p-methoxyphenyl-1H-pyrazolyl-5-carboxylate in pharmacy | UNIV SHANDONG | 2015-08-05 | — | — | CN | claimed |
| CN-104814956-A | Use of ethyl (S)-1-(3-p-chlorophenoxy-2-hydroxypropyl)-3-p-methoxyphenyl-1H-pyrazolyl-5-carboxylate in pharmacy | UNIV SHANDONG | 2015-08-05 | — | — | CN | disclosed |