Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HGFAC | Q04756 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619337 | 0.85 | GPR35 (0.55) | KMT2APKMGPR35POLBALDH1A1 | |
| SCHEMBL30459424 | 0.85 | GPR35 (0.55) | KMT2APKMGPR35POLBALDH1A1 | |
| SCHEMBL7330798 | 0.84 | MAPT (0.56) | KMT2APOLBALDH1A1MAPTMEN1 | |
| SCHEMBL10747235 | 0.82 | RECQL (0.52) | PKMGPR35POLBALDH1A1TP53 | |
| SCHEMBL27811580 | 0.81 | GPR35 (0.50) | KMT2APKMGPR35ALDH1A1MAPT | |
| SCHEMBL11751170 | 0.79 | ALOX5 (0.57) | HGFACKMT2AALOX5ALDH1A1MAPT | |
| SCHEMBL28982636 | 0.78 | ALOX5 (0.57) | HGFACKMT2AGPR35ALOX5POLB | |
| SCHEMBL27459058 | 0.78 | CES2 (0.51) | KMT2AGPR35ALOX5POLBALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27995845 | 0.78 | CES2 (0.58) | HGFACKMT2AALOX5ALDH1A1MAPT | |
| SCHEMBL8614465 | 0.78 | HGFAC (0.50) | HGFACKMT2APKMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693057-A | Preparation method of 2,5-diamino terephthalic acid | SHANGHAI INST TECHNOLOGY | 2015-06-10 | — | — | CN | claimed |
| CN-104693057-A | Preparation method of 2,5-diamino terephthalic acid | SHANGHAI INST TECHNOLOGY | 2015-06-10 | — | — | CN | disclosed |