Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025017 | 0.91 | RAB9A (0.51) | HCRTR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28206980 | 0.85 | RAB9A (0.52) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL28025005 | 0.85 | RAB9A (0.52) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6824483 | 0.84 | MEN1 (0.54) | HCRTR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19322279 | 0.84 | GAA (0.70) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28024557 | 0.82 | NR4A2 (0.49) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19322277 | 0.82 | ALDH1A1 (0.60) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23863044 | 0.81 | HCRTR1 (0.60) | HCRTR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19322278 | 0.79 | NR4A2 (0.50) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28025008 | 0.79 | ALOX5 (0.56) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892485-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-09-09 | — | — | CN | disclosed |