Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLD2 | O14939 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206980 | 0.90 | RAB9A (0.52) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL28024559 | 0.90 | RAB9A (0.52) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL28024563 | 0.85 | HCRTR1 (0.56) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL28206987 | 0.85 | KIF11 (0.47) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL28024557 | 0.84 | NR4A2 (0.49) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL19322278 | 0.83 | NR4A2 (0.50) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL28025008 | 0.83 | ALOX5 (0.56) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL28025014 | 0.82 | KDM4E (0.51) | RAB9ANPC1KDM4EKIF11MEN1 | |
| SCHEMBL20867843 | 0.79 | NR4A2 (0.63) | KDM4EALDH1A1HPGDHSD17B10KIF11 | |
| SCHEMBL28207450 | 0.79 | RAB9A (0.52) | RAB9ANPC1KDM4EALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104892485-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-09-09 | — | — | CN | disclosed |