Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137068 | 0.78 | LMNA (0.47) | KDM4ELMNAALDH1A1PIK3C3 | |
| SCHEMBL2082554 | 0.73 | LMNA (0.55) | KDM4ELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL29199444 | 0.72 | LMNA (0.53) | KDM4ELMNAALDH1A1 | |
| SCHEMBL28025174 | 0.71 | CHRNB2 (0.41) | PIK3C3 | |
| SCHEMBL28024733 | 0.64 | POLB (0.35) | KDM4ELMNAALDH1A1 | |
| SCHEMBL2082574 | 0.63 | CHKA (0.43) | KDM4ELMNAALDH1A1 | |
| SCHEMBL28025203 | 0.63 | ATR (0.35) | KDM4EALDH1A1PIK3C3 | |
| SCHEMBL17292797 | 0.63 | PIK3C3 (0.32) | PIK3C3 | |
| SCHEMBL18110383 | 0.62 | NR3C2 (0.33) | LMNA | |
| SCHEMBL30206003 | 0.61 | AKR1C3 (0.46) | HTR3AKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |