Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025174 | 0.75 | CHRNB2 (0.41) | MAPTHTT | |
| SCHEMBL137068 | 0.73 | LMNA (0.47) | AKR1C3MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL28024746 | 0.70 | PIK3CD (0.36) | KDM4EALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL16332686 | 0.68 | PIK3C3 (0.44) | PIK3CDPIK3CA | |
| SCHEMBL16332803 | 0.68 | PIK3C3 (0.44) | PIK3CDPIK3CA | |
| SCHEMBL23103865 | 0.66 | PIK3C3 (0.46) | PIK3CA | |
| SCHEMBL17055234 | 0.65 | MTOR (0.55) | PIK3CDPIK3CA | |
| SCHEMBL20917110 | 0.65 | MTOR (0.55) | PIK3CDPIK3CA | |
| SCHEMBL27965766 | 0.65 | MTOR (0.55) | PIK3CDPIK3CA | |
| SCHEMBL25147362 | 0.65 | PIK3C3 (0.44) | PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |