Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710630 | 0.83 | LMNA (0.51) | MAPTALDH1A1TP53GAACYP1A2 | |
| SCHEMBL29111812 | 0.83 | KMT2A (0.46) | MAPTALDH1A1CYP1A2HSD17B10KMT2A | |
| SCHEMBL15300224 | 0.82 | MAPT (0.47) | MAPTALDH1A1L3MBTL1TP53HSD17B10 | |
| SCHEMBL31273808 | 0.81 | HSD17B10 (0.52) | MAPTALDH1A1GAACYP1A2HSD17B10 | |
| SCHEMBL28508119 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1L3MBTL1TP53GAA | |
| SCHEMBL31275168 | 0.79 | KIF11 (0.47) | MAPTALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL28787723 | 0.74 | ALDH1A1 (0.33) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL28696144 | 0.74 | — | — | |
| SCHEMBL27438012 | 0.73 | MAPT (0.44) | MAPTALDH1A1TP53GAACYP1A2 | |
| SCHEMBL28490620 | 0.71 | MAPT (0.66) | MAPTALDH1A1L3MBTL1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061315-B | 1, 5-diphenylpyrazole-3-carboxylic acid compounds and application thereof | 大连理工大学 | 2017-10-24 | — | — | CN | disclosed |
| CN-105142635-A | Heterocyclic compounds useful in treatment of disease | EPIGEN BIOSCIENCES INC | 2015-12-09 | — | — | CN | disclosed |