Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025010 | 0.90 | GAA (0.53) | KDM4EGAAGLANR4A2MEN1 | |
| SCHEMBL28206986 | 0.85 | KDM4E (0.52) | KDM4EGAATRPA1MEN1KMT2A | |
| SCHEMBL28025012 | 0.83 | NR4A2 (0.49) | KDM4EGAANR4A2MEN1KMT2A | |
| SCHEMBL28025015 | 0.82 | NR4A2 (0.50) | KDM4EGAANR4A2MEN1KMT2A | |
| SCHEMBL28206982 | 0.81 | PBRM1 (0.42) | KDM4ENR4A2MEN1KMT2AALDH1A1 | |
| SCHEMBL28206985 | 0.77 | KDM4E (0.56) | KDM4EGAAGLAMEN1KMT2A | |
| SCHEMBL28024562 | 0.77 | LMNA (0.52) | KDM4EGAAALDH1A1HPGDNPSR1 | |
| SCHEMBL20867843 | 0.75 | NR4A2 (0.63) | KDM4ENR4A2MEN1KMT2AALDH1A1 | |
| SCHEMBL28025014 | 0.73 | KDM4E (0.51) | KDM4EGAANR4A2MEN1KMT2A | |
| SCHEMBL28024552 | 0.73 | KIF11 (0.49) | KDM4EGAANR4A2TRPA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104892485-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-09-09 | — | — | CN | disclosed |