Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25984970 | 0.75 | HDAC4 (0.42) | HDAC4GLSCYP11B1CYP11B2 | |
| SCHEMBL28053556 | 0.74 | LMNA (0.41) | HDAC4ALDH1A1F2GLAHPGD | |
| SCHEMBL28024734 | 0.73 | GLA (0.41) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL28025218 | 0.73 | GLA (0.41) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL16094460 | 0.71 | ATM (0.44) | HDAC4ALDH1A1HPGDLMNACYP11B1 | |
| SCHEMBL28025226 | 0.69 | ALDH1A1 (0.38) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL28025234 | 0.66 | HDAC4 (0.43) | HDAC4ALDH1A1HPGDMAPTLMNA | |
| SCHEMBL27718082 | 0.66 | MAPT (0.42) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL4443112 | 0.65 | LMNA (0.55) | ALDH1A1GLAMAPTLMNACYP3A4 | |
| SCHEMBL20674585 | 0.65 | SMN1; SMN2 (0.40) | HDAC4ALDH1A1MAPTKMT2AGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |