SCHEMBL28025538

SCHEMBL28025538

[CH]1C=C(c2ccoc2)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.38
NAT1 P18440 3/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CLK4 Q9HAZ1 2/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
KMT2A Q03164 1/20 0.32
ADORA2A P29274 1/20 0.32
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
ACHE P22303 1/20 0.31
FYN P06241 1/20 0.31
CNR2 P34972 1/20 0.31
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5076754 0.76 ALDH1A1 (0.41) ALDH1A1HSD17B10
SCHEMBL5824297 0.75 MEN1 (0.32) ALDH1A1HSD17B10MEN1KMT2AACHE
SCHEMBL28303649 0.74 ALDH1A1 (0.39) ALDH1A1HSD17B10
SCHEMBL28515419 0.71 NPC1 (0.39) ALDH1A1MEN1KMT2AACHETSHR
SCHEMBL28025966 0.69 PTGS2 (0.38) ALDH1A1MEN1KMT2A
SCHEMBL28219408 0.69 ALDH1A1 (0.36) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL28025982 0.69 CYP1A2 (0.43) ALDH1A1CYP1A2CYP2C19HSD17B10MEN1
SCHEMBL27502471 0.69 ALDH1A1 (0.35) ALDH1A1HSD17B10KMT2A
SCHEMBL28025423 0.68 BRD9 (0.34) MEN1KMT2AADORA2AACHETSHR
SCHEMBL28025432 0.68 KDM4E (0.38) ALDH1A1HSD17B10MEN1USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed