SCHEMBL28025966

SCHEMBL28025966

Fc1ccc(C2=C[CH]c3ccccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.38
PTGS1 P23219 1/20 0.38
PTAFR P25105 1/20 0.36
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
NR4A2 P43354 1/20 0.34
MAPK14 Q16539 1/20 0.34
HTR7 P34969 1/20 0.34
NPC1 O15118 2/20 0.33
AR P10275 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
MAOB P27338 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5076754 0.83 ALDH1A1 (0.41) ALDH1A1MAOB
SCHEMBL28025517 0.82 CNR1 (0.33)
SCHEMBL28515419 0.82 NPC1 (0.39) PTAFRNPC1ALDH1A1MAPTRAB9A
SCHEMBL28303649 0.81 ALDH1A1 (0.39) ALDH1A1MAOB
SCHEMBL28025982 0.80 CYP1A2 (0.43) PTGS2PTGS1PTAFRSLC6A4SLC6A3
SCHEMBL28025419 0.79 TAAR1 (0.39) HTR7MAPTMAOBSMN1; SMN2PDK2
SCHEMBL28515991 0.79 KIF11 (0.48) ALDH1A1MAPTMAOB
SCHEMBL28025430 0.79 MAOB (0.39) ALDH1A1MAPTMAOBRAB9A
SCHEMBL5824297 0.78 MEN1 (0.32) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL28506923 0.77 MAP2K4 (0.34) PTGS1ARALDH1A1MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed