Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942832 | 0.81 | CA12 (0.59) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL9762303 | 0.80 | CA1 (0.51) | KMT2AALDH1A1MAPTCA12CA1 | |
| SCHEMBL11754900 | 0.79 | MTOR (0.72) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL7608931 | 0.79 | MTOR (0.57) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL251878 | 0.79 | MTOR (0.56) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL6206532 | 0.78 | SMN1; SMN2 (0.56) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL11070019 | 0.78 | TAS2R38 (0.48) | MEN1KMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL9340888 | 0.78 | MTOR (0.56) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL27342617 | 0.76 | MTOR (0.58) | MTORMEN1KMT2AHSD17B10NAPRT | |
| SCHEMBL11617578 | 0.74 | MEN1 (0.62) | MTORMEN1KMT2AHSD17B10NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858767-B | As the aminopyrimidine of SYK inhibitor | MERCK SHARP & DOHME CORP. (US) | 2015-08-19 | — | — | CN | disclosed |