Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026374 | 0.81 | SMN1; SMN2 (0.53) | LMNAELANEALDH1A1GAAMEN1 | |
| SCHEMBL28026378 | 0.81 | ALDH1A1 (0.54) | LMNAELANEALDH1A1GAAMEN1 | |
| SCHEMBL30415002 | 0.81 | MAPT (0.62) | MAPTTP53LMNAARPKM | |
| SCHEMBL20267468 | 0.81 | MAPT (0.62) | MAPTTP53LMNAARPKM | |
| SCHEMBL29712314 | 0.79 | ALDH1A1 (0.63) | MAPTTP53LMNAARPKM | |
| SCHEMBL21462498 | 0.79 | ALDH1A1 (0.63) | MAPTTP53LMNAARPKM | |
| SCHEMBL28025828 | 0.78 | ALDH1A1 (0.59) | MAPTLMNAELANEALDH1A1GAA | |
| SCHEMBL9400659 | 0.78 | MAPT (0.78) | MAPTTP53LMNAARPKM | |
| SCHEMBL29712306 | 0.78 | MAPT (0.61) | MAPTTP53LMNAARPKM | |
| SCHEMBL20567987 | 0.78 | MAPT (0.61) | MAPTTP53LMNAARPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945303-A | Preparation method of 3-alkenyl indole compound | UNIV ZHEJIANG TECHNOLOGY | 2015-09-30 | — | — | CN | disclosed |