Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026378 | 0.85 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL21954348 | 0.83 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL28025828 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL28025829 | 0.81 | MAPT (0.61) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL28026401 | 0.81 | MAPT (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL25941571 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL22528411 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL3206351 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL18548900 | 0.78 | LMNA (0.58) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL15966805 | 0.77 | ALDH1A1 (0.77) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945303-A | Preparation method of 3-alkenyl indole compound | UNIV ZHEJIANG TECHNOLOGY | 2015-09-30 | — | — | CN | disclosed |