Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026374 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL28025828 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL28025829 | 0.81 | MAPT (0.61) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL11313274 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL14848304 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL5530559 | 0.77 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL7414503 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL7511323 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL7387558 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL8688754 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945303-A | Preparation method of 3-alkenyl indole compound | UNIV ZHEJIANG TECHNOLOGY | 2015-09-30 | — | — | CN | disclosed |