Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL28025843 | 0.93 | HTT (0.54) | NAAAEPHX1ALDH1A1HTTMGLL | |
| Bromobenzene SCHEMBL28310421 | 0.86 | L3MBTL1 (0.56) | L3MBTL1HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL1003218 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL8979293 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL1481880 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL25243376 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL14002535 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL7990903 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL2481694 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A | |
| SCHEMBL559951 | 0.80 | KDM4E (0.80) | NAAAEPHX1KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817485-A | Isoindigo derivative and preparation method thereof | UNIV ANHUI NORMAL | 2015-08-05 | — | — | CN | claimed |
| CN-104817485-A | Isoindigo derivative and preparation method thereof | UNIV ANHUI NORMAL | 2015-08-05 | — | — | CN | disclosed |