Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL28025852 | 0.93 | NAAA (0.59) | HTTL3MBTL1NAAAMGLLEPHX1 | |
| Bromobenzene SCHEMBL28310421 | 0.89 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BCYP1A2CYP2C19 | |
| Catechol SCHEMBL27318195 | 0.82 | HTT (0.58) | HTTTSHRL3MBTL1MTNR1AMTNR1B | |
| Bromobenzene SCHEMBL27841763 | 0.82 | MTNR1A (0.49) | L3MBTL1MTNR1AMTNR1BCYP1A2CYP2C19 | |
| Acetanilide SCHEMBL3463848 | 0.81 | NAPRT (0.63) | HTTTSHRL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL48873 | 0.79 | — | — | |
| SCHEMBL28726702 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28190096 | 0.77 | KDM4E (0.67) | HTTTSHREPHX1 | |
| SCHEMBL5511446 | 0.77 | — | — | |
| Propionic Acid SCHEMBL715424 | 0.75 | KDM4E (0.58) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817485-A | Isoindigo derivative and preparation method thereof | UNIV ANHUI NORMAL | 2015-08-05 | — | — | CN | claimed |
| CN-104817485-A | Isoindigo derivative and preparation method thereof | UNIV ANHUI NORMAL | 2015-08-05 | — | — | CN | disclosed |