SCHEMBL28025955

SCHEMBL28025955

Fc1cccc(C2=C[CH]c3ccccc32)c1F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
BCAT1 P54687 1/20 0.32
CES2 O00748 1/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5824297 0.76 MEN1 (0.32) CES2BCHECES1
SCHEMBL17293173 0.76
SCHEMBL28515923 0.74 GPR3 (0.38)
SCHEMBL3038641 0.71 CES2 (0.46) HSD11B1BCAT1CES2BCHECES1
SCHEMBL7644097 0.71 PTPN1 (0.44)
SCHEMBL2959608 0.70 HSD11B1 (0.38) HSD11B1BCAT1
SCHEMBL28515390 0.69 NPC1 (0.38)
SCHEMBL1784457 0.69 NPC1 (0.42) HSD11B1BCAT1CES2BCHECES1
SCHEMBL28521495 0.69 TRPA1 (0.34)
SCHEMBL28521719 0.69 HSD11B1 (0.41) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed