SCHEMBL28026052

SCHEMBL28026052

COC(=O)C(C)(CCC=O)C[SH](=O)=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28166450 1.00 DGAT1 (0.31) DGAT1
SCHEMBL28848783 0.81 CYP2D6 (0.35)
SCHEMBL3183165 0.75 DGAT1 (0.35) DGAT1
SCHEMBL27359921 0.75 DGAT1 (0.35) DGAT1
SCHEMBL28166601 0.71 PKM (0.35)
SCHEMBL27725175 0.70 TSHR (0.38) DGAT1
SCHEMBL6372189 0.69 CYP4F2 (0.39) DGAT1
SCHEMBL31405859 0.69 DGAT1 (0.31) DGAT1
SCHEMBL7436601 0.68 CYP4F2 (0.38)
SCHEMBL28026053 0.68 DGAT1 (0.34) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103717582-B As the different * oxazole derivatives of antiseptic-germicide PFIZER INC. (US) 2015-09-30 CN disclosed