Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21189700 | 0.77 | CHRM2 (0.36) | ALDH1A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL27432645 | 0.74 | KEAP1 (0.48) | MAPTTDP1CYP2D6CHRM2CHRM1 | |
| SCHEMBL29833702 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL291792 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL27721857 | 0.69 | TRPA1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL668814 | 0.67 | TRPA1 (0.47) | ALDH1A1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL6981900 | 0.67 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL547913 | 0.67 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL2267090 | 0.67 | TRPA1 (0.47) | ALDH1A1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL5605717 | 0.67 | ALDH1A1 (0.43) | ALDH1A1TDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926765-A | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | MERCK PATENT GMBH | 2015-09-23 | — | — | CN | disclosed |