Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952161 | 0.87 | TYR (0.35) | KDM4ECA12CA1CA2GAA | |
| SCHEMBL6987657 | 0.83 | HTR2B (0.42) | KDM4EMAPTALDH1A1THRBHPGD | |
| SCHEMBL6314485 | 0.81 | KDM4E (0.40) | KDM4ECA12CA1CA2POLB | |
| SCHEMBL6314483 | 0.81 | KDM4E (0.40) | KDM4ECA12CA1CA2POLB | |
| SCHEMBL6982545 | 0.74 | ALOX5 (0.33) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6988447 | 0.74 | ALOX5 (0.33) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6985040 | 0.73 | KDM4E (0.40) | KDM4ECA12CA1CA2MAPT | |
| SCHEMBL6989995 | 0.70 | MEN1 (0.39) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL6419881 | 0.69 | HTR2B (0.36) | KDM4EGAATTRHTTALDH1A1 | |
| SCHEMBL18197335 | 0.68 | MAPT (0.42) | KDM4ECA2GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302467-A2 | Process for the preparation of substituted thiazoline derivatives and their intermediate | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-04-16 | — | — | EP | disclosed |