Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145757 | 0.81 | ALDH1A1 (0.54) | TDP1 | |
| SCHEMBL2195053 | 0.77 | NFE2L2 (0.54) | — | |
| SCHEMBL9129790 | 0.75 | PARP15 (0.41) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL17142065 | 0.75 | PARP15 (0.48) | PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL29024848 | 0.73 | PARP15 (0.64) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL8930160 | 0.72 | PARP15 (0.55) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL2665020 | 0.72 | PARP15 (0.55) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL28413630 | 0.71 | PARP15 (0.53) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL15776314 | 0.70 | BRD4 (0.37) | — | |
| SCHEMBL8273728 | 0.69 | PARP15 (0.51) | PARP15PARP10PARP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-B | It can be used as the acid amides of pyridine 2 of CB2 activators | 霍夫曼-拉罗奇有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |