Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.53 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22667286 | 0.86 | CUL4A (0.68) | PARK7CUL4ACES1ACHEALDH1A1 | |
| SCHEMBL30403461 | 0.86 | CUL4A (0.68) | PARK7CUL4ACES1ACHEALDH1A1 | |
| SCHEMBL28417115 | 0.84 | ALDH1A1 (0.57) | CUL4ACES1ACHEALDH1A1ALDH2 | |
| SCHEMBL28417285 | 0.82 | CES1 (0.65) | CUL4ACES1ACHEALDH1A1ALDH2 | |
| SCHEMBL6176718 | 0.81 | ALDH1A1 (0.45) | CUL4ACES1ACHEALDH1A1ALDH2 | |
| SCHEMBL16075218 | 0.80 | ALDH1A1 (0.47) | CUL4ACES1ACHEALDH1A1ALDH2 | |
| SCHEMBL16064931 | 0.80 | ALDH1A1 (0.47) | CUL4ACES1ACHEALDH1A1ALDH2 | |
| SCHEMBL16064397 | 0.80 | ALDH1A1 (0.47) | PARK7CUL4ACES1ACHEALDH1A1 | |
| SCHEMBL29411355 | 0.79 | APAF1 (0.60) | PARK7CES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL25865292 | 0.79 | ACHE (0.47) | PARK7CUL4ACES1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798230-A | Indolone compounds and application thereof in treating acute and chronic liver diseases and promoting tissue repair | 中国药科大学 | 2025-04-11 | — | — | CN | claimed |
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
| CN-119798230-A | Indolone compounds and application thereof in treating acute and chronic liver diseases and promoting tissue repair | 中国药科大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-104829608-A | Coumarin-thiazole-indolone compounds, and preparation method and application thereof | UNIV JISHOU | 2015-08-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP9, DPP7, DPP4 | PARK7 1549/4885CUL4A 2346/4885CES1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.