Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360302 | 0.81 | LMNA (0.78) | LMNASMN1; SMN2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL6806147 | 0.79 | LMNA (0.53) | LMNASMN1; SMN2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL3691082 | 0.77 | LMNA (0.55) | LMNASMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL8658127 | 0.77 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL439716 | 0.76 | LMNA (0.59) | LMNASMN1; SMN2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL3698437 | 0.73 | LMNA (0.50) | LMNASMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL4548036 | 0.73 | LMNA (0.61) | LMNASMN1; SMN2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL3439357 | 0.72 | KDM4E (0.51) | LMNASMN1; SMN2TDP1ALDH1A1CYP1A2 | |
| SCHEMBL1346262 | 0.72 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2ALDH1A1CYP3A4HTR6 | |
| SCHEMBL105629 | 0.71 | LMNA (0.55) | LMNASMN1; SMN2TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844575-A | 2-pyrimidinyloxy-N-arylazabenzylamine compound, preparation method, herbicide and application thereof | SHANGHAI INSITITUTE OF ORGANIC CHEMISTRY CHINESE ACADEMY OF SCIENCES | 2015-08-19 | — | — | CN | disclosed |