Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186786 | 0.75 | TSHR (0.40) | — | |
| SCHEMBL11561999 | 0.75 | MAPT (0.34) | — | |
| SCHEMBL15740565 | 0.75 | MAPT (0.34) | — | |
| SCHEMBL2551773 | 0.75 | GAA (0.34) | HRH3 | |
| SCHEMBL31325065 | 0.69 | HTR1A (0.32) | — | |
| SCHEMBL43356 | 0.68 | GPR35 (0.38) | — | |
| SCHEMBL319993 | 0.65 | — | — | |
| SCHEMBL9324324 | 0.65 | — | — | |
| SCHEMBL11561961 | 0.65 | — | — | |
| SCHEMBL28116330 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955824-A | Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants | GENENTECH INC | 2015-09-30 | — | — | CN | disclosed |