Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026945 | 0.76 | MAOB (0.40) | HPGDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4607913 | 0.69 | P2RX7 (0.40) | ALDH1A1TSHRHPGDGRIN2DGRIN3B | |
| SCHEMBL28313136 | 0.67 | MAOB (0.42) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6687826 | 0.67 | GRIN2D (0.39) | OPRK1ALDH1A1TSHRHPGDGRIN2D | |
| SCHEMBL21002245 | 0.67 | CNR2 (0.38) | OPRK1HPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5561167 | 0.66 | KDM1A (0.38) | ALDH1A1HPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5475255 | 0.64 | HSD11B1 (0.44) | ALDH1A1TSHRHPGDP2RX7HSD11B1 | |
| SCHEMBL27966414 | 0.64 | HSD11B1 (0.37) | ALDH1A1TSHRHPGDGRIN2DGRIN3B | |
| SCHEMBL14350740 | 0.64 | SLC6A2 (0.40) | — | |
| SCHEMBL14350741 | 0.63 | SLC6A2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104840975-B | A kind of super-molecule assembling body and preparation method of targeted delivery siRNA | 南开大学 | 2018-01-23 | — | — | CN | claimed |
| CN-104840975-A | Supermolecular assembly for small interfering RNA targeting delivery and preparation method | UNIV NANKAI | 2015-08-19 | — | — | CN | claimed |
| CN-104840975-B | A kind of super-molecule assembling body and preparation method of targeted delivery siRNA | 南开大学 | 2018-01-23 | — | — | CN | disclosed |
| CN-104840975-A | Supermolecular assembly for small interfering RNA targeting delivery and preparation method | UNIV NANKAI | 2015-08-19 | — | — | CN | disclosed |