SCHEMBL5475255

SCHEMBL5475255

O=C(O)C1C2CC3CC(C2)CC1(c1ccccc1)C3

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.44
KDM4E B2RXH2 2/20 0.43
P2RX7 Q99572 5/20 0.43
HPGD P15428 1/20 0.42
FAAH O00519 1/20 0.41
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
LMNA P02545 1/20 0.40
EPHX2 P34913 2/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAPK1 P28482 2/20 0.38
HSD11B2 P80365 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4607913 0.79 P2RX7 (0.40) HSD11B1KDM4EP2RX7HPGDFAAH
SCHEMBL27966414 0.77 HSD11B1 (0.37) HSD11B1KDM4EP2RX7HPGDFAAH
SCHEMBL7523253 0.74 FAAH (0.45) FAAHEPHX2MEN1KMT2A
SCHEMBL2746956 0.74 THRB (0.38) HSD11B1P2RX7HPGDFAAHALDH1A1
SCHEMBL6687826 0.74 GRIN2D (0.39) HSD11B1KDM4EP2RX7HPGDFAAH
SCHEMBL28313136 0.74 MAOB (0.42) P2RX7ALDH1A1LMNA
SCHEMBL7523248 0.73 EPHX2 (0.43) HSD11B1KDM4EP2RX7HPGDFAAH
SCHEMBL5561167 0.72 KDM1A (0.38) P2RX7HPGDFAAHALDH1A1LMNA
SCHEMBL8064643 0.71 MEN1 (0.50) FAAHCNR2ALDH1A1EPHX2MEN1
SCHEMBL19149356 0.70 NPC1 (0.43) HSD11B1FAAHALDH1A1LMNAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070191585-A1 Organic polymer film and method for forming the same PANASONIC CORPORATION (JP) 2007-08-16 US disclosed