Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 3/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151362 | 0.80 | KDM1A (0.46) | P2RX7EPHX2GRIN2BHSD11B1 | |
| SCHEMBL30688050 | 0.80 | KDM1A (0.46) | P2RX7EPHX2GRIN2BHSD11B1 | |
| SCHEMBL6687826 | 0.79 | GRIN2D (0.39) | P2RX7GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28313136 | 0.79 | MAOB (0.42) | P2RX7GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5475255 | 0.79 | HSD11B1 (0.44) | P2RX7EPHX2MEN1KMT2ANPSR1 | |
| SCHEMBL5561167 | 0.78 | KDM1A (0.38) | P2RX7GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29065708 | 0.78 | EPHX2 (0.47) | P2RX7EPHX2MEN1KMT2AFAAH | |
| SCHEMBL7083692 | 0.75 | SIGMAR1 (0.39) | P2RX7GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7081986 | 0.75 | P2RX7 (0.39) | P2RX7NPSR1HSD11B1CNR2HTT | |
| SCHEMBL27966414 | 0.75 | HSD11B1 (0.37) | P2RX7EPHX2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | claimed |
| CN-116444438-B | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2024-02-13 | — | — | CN | disclosed |
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | disclosed |
| CN-116444438-A | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2023-07-18 | — | — | CN | disclosed |
| CN-107266319-A | Dendritic polyphenyl substituted adamantane derivative monomolecular resin, positive photoresist composition and negative photoresist composition | 中国科学院理化技术研究所 | 2017-10-20 | — | — | CN | disclosed |
| EP-1336597-B1 | Hydroxyphenyl adamantanes and process for the production of the same | HONSHU CHEMICAL IND (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-1336597-A1 | Hydroxyphenyl adamantanes and process for the production of the same | Honshu Chemical Industry Co., Ltd. (JP) | 2003-08-20 | — | — | EP | disclosed |