Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027599 | 0.91 | LMNA (0.47) | LMNAMEN1KMT2AGAAHTT | |
| SCHEMBL28026970 | 0.91 | LMNA (0.53) | LMNAMEN1KMT2AGAAHTT | |
| SCHEMBL28027600 | 0.83 | LMNA (0.53) | LMNAMEN1KMT2AGAAHTT | |
| SCHEMBL10170773 | 0.78 | TAS1R3 (0.40) | MEN1KMT2AHTTALDH1A1TAS1R3 | |
| SCHEMBL675390 | 0.78 | TAS1R3 (0.40) | MEN1KMT2AHTTALDH1A1TAS1R3 | |
| SCHEMBL22267 | 0.78 | TAS1R3 (0.40) | MEN1KMT2AHTTALDH1A1TAS1R3 | |
| SCHEMBL3030564 | 0.78 | TAS1R3 (0.40) | MEN1KMT2AHTTALDH1A1TAS1R3 | |
| SCHEMBL6648721 | 0.78 | TAS1R3 (0.40) | MEN1KMT2AHTTALDH1A1TAS1R3 | |
| SCHEMBL8415723 | 0.77 | HTT (0.54) | LMNAMEN1KMT2AHTT | |
| SCHEMBL27929191 | 0.76 | LMNA (0.45) | LMNAMEN1KMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103408465-B | A kind of N-disubstituted benzenes ylmethyl valine amide carbamate derivatives and application | NANKAI UNIVERSITY (CN) | 2015-08-26 | — | — | CN | claimed |