Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027599 | 0.87 | LMNA (0.47) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9331274 | 0.83 | CTSK (0.53) | HTTMEN1KMT2A | |
| SCHEMBL28027600 | 0.82 | LMNA (0.53) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7564627 | 0.81 | HTT (0.47) | HTTTSHRCASP3CASP8MME | |
| SCHEMBL9828845 | 0.77 | HTT (0.57) | HTTTSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL9828837 | 0.77 | HTT (0.57) | HTTTSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL28026970 | 0.77 | LMNA (0.53) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28026971 | 0.77 | LMNA (0.47) | HTTMEN1KMT2ALMNA | |
| SCHEMBL8576836 | 0.76 | MMP9 (0.53) | HTTMEN1KMT2AHPGDS | |
| SCHEMBL6917355 | 0.76 | MMP9 (0.53) | HTTMEN1KMT2AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942541-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-24 | — | — | US | disclosed |
| US-5723646-A | Substituted amino acid amide derivatives their preparation and use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0587110-B1 | Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0496239-B1 | Substituted aminoacid amide derivatives, their preparation and use as fungicide | BAYER AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| US-5348976-A | Amide derivatives as fungicides safe for plants | KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-09-20 | — | — | US | disclosed |
| EP-0587110-A2 | Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0496239-A2 | Substituted aminoacid amide derivatives, their preparation and use as fungicide | BAYER AG (DE) | 1992-07-29 | — | — | EP | disclosed |