Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | C5 | P01031 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027599 | 0.92 | LMNA (0.47) | LMNASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL28026971 | 0.83 | LMNA (0.47) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL28026970 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2KMT2APOLBALDH1A1 | |
| SCHEMBL8415723 | 0.82 | HTT (0.54) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL27946588 | 0.78 | LMNA (0.50) | LMNASMN1; SMN2KMT2APOLBALDH1A1 | |
| SCHEMBL27929194 | 0.71 | LMNA (0.50) | LMNASMN1; SMN2KMT2APOLBALDH1A1 | |
| SCHEMBL14479048 | 0.70 | CA1 (0.56) | SMN1; SMN2KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL7174425 | 0.69 | PDE4A (0.53) | LMNASMN1; SMN2KMT2APOLBNPSR1 | |
| SCHEMBL4825769 | 0.69 | PDE4D (0.64) | LMNASMN1; SMN2KMT2APOLBNPSR1 | |
| SCHEMBL7183447 | 0.69 | PDE4A (0.64) | LMNASMN1; SMN2KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103408465-B | A kind of N-disubstituted benzenes ylmethyl valine amide carbamate derivatives and application | NANKAI UNIVERSITY (CN) | 2015-08-26 | — | — | CN | claimed |