Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | CALML3 | P27482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027390 | 0.80 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL28028084 | 0.77 | TGFBR1 (0.40) | ALDH1A1PRKCITGFBR1CNR2PARP1 | |
| SCHEMBL28027971 | 0.76 | FFAR1 (0.35) | FFAR1GRM2 | |
| SCHEMBL28027431 | 0.76 | CD274 (0.42) | ALDH1A1PRKCITGFBR1CNR2PDCD1 | |
| SCHEMBL28838506 | 0.75 | PRKCI (0.38) | ALDH1A1PRKCITGFBR1CNR2PDCD1 | |
| SCHEMBL28027950 | 0.72 | ALDH1A1 (0.35) | ALDH1A1PRKCITGFBR1CNR2PDCD1 | |
| SCHEMBL28027986 | 0.72 | MAOA (0.41) | PRKCICNR2KDM4EMAP2K4 | |
| SCHEMBL28122540 | 0.71 | PRKCI (0.37) | ALDH1A1PRKCITGFBR1CNR2PDCD1 | |
| SCHEMBL3451644 | 0.70 | PRKCI (0.49) | PRKCITGFBR1CNR2FFAR1MAP2K4 | |
| SCHEMBL1508340 | 0.70 | HTR7 (0.59) | PRKCICNR2FFAR1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |