Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.75 |
| ▸ | NPC1 | O15118 | 10/20 | 0.75 |
| ▸ | RAB9A | P51151 | 10/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | TP53 | P04637 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.62 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417301 | 0.98 | NPC1 (0.78) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17470481 | 0.93 | NPC1 (0.76) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12153689 | 0.90 | NPC1 (0.77) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15497747 | 0.88 | NPC1 (0.74) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7395100 | 0.86 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1284008 | 0.86 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4582557 | 0.86 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2243332 | 0.86 | ALDH1A1 (0.67) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3335064 | 0.86 | NPC1 (0.67) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13816864 | 0.86 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175344-A | 1,3-bis-benzimidazolyl benzene silver (I) complex and application thereof to pharmacy | UNIV GUANGXI MEDICAL | 2015-12-23 | — | — | CN | disclosed |
| CN-105175344-A | 1,3-bis-benzimidazolyl benzene silver (I) complex and application thereof to pharmacy | UNIV GUANGXI MEDICAL | 2015-12-23 | — | — | CN | disclosed |