SCHEMBL3417301

SCHEMBL3417301

c1cc(-c2nc3ccccc3[nH]2)cc(-c2nc3ccccc3[nH]2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.78
RAB9A P51151 10/20 0.78
GAA P10253 2/20 0.78
KDM4E B2RXH2 11/20 0.77
SMN1; SMN2 Q16637 10/20 0.77
ALDH1A1 P00352 9/20 0.77
HPGD P15428 5/20 0.77
HSD17B10 Q99714 4/20 0.77
TP53 P04637 3/20 0.77
PKM P14618 3/20 0.69
ABCB11 O95342 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
MAPT P10636 5/20 0.66
USP2 O75604 2/20 0.66
TDP1 Q9NUW8 1/20 0.66
PKN1 Q16512 1/20 0.65
PKN2 Q16513 1/20 0.65
POLB P06746 4/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28027557 0.98 KDM4E (0.75) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL17470481 0.94 NPC1 (0.76) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL12153689 0.92 NPC1 (0.77) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL15497747 0.90 NPC1 (0.74) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL4582557 0.88 KDM4E (0.67) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL7395100 0.88 KDM4E (0.67) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL2243332 0.88 ALDH1A1 (0.67) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL4122566 0.88 NPC1 (0.68) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL1284008 0.88 KDM4E (0.67) NPC1RAB9AGAAKDM4ESMN1; SMN2
SCHEMBL13816864 0.88 KDM4E (0.67) NPC1RAB9AGAAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115233374-B Fiber composite material and preparation method and application thereof 深圳麦克韦尔科技有限公司 2024-04-16 CN claimed
US-11913140-B2 Phosphonated PBI fiber PBI Performance Products (US) 2024-02-27 US claimed
WO-2024026930-A1 FIBER COMPOSITE MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳麦克韦尔科技有限公司 2024-02-08 WO claimed
CN-115233374-A Fiber composite material and preparation method and application thereof 深圳麦克韦尔科技有限公司 2022-10-25 CN claimed
JP-62091414-A None JP disclosed
US-12636618-B1 Asymmetric carbon molecular sieve hollow fiber membranes TRIAD NATIONAL SECURITY, LLC (US) 2026-05-26 US disclosed
US-12065763-B2 Method of making a phosphonated PBI fiber PBI PERFORMANCE PRODUCTS, INC. (US) 2024-08-20 US disclosed
US-20240269649-A1 Porous Polymer Product For Removing Contaminants From A Fluid Stream CELANESE INTERNATIONAL CORPORATION 2024-08-15 US disclosed
US-11959196-B2 Phosphonated PBI fiber PBI PERFORMANCE PRODUCTS, INC. (US) 2024-04-16 US disclosed
CN-115233374-B Fiber composite material and preparation method and application thereof 深圳麦克韦尔科技有限公司 2024-04-16 CN disclosed
US-11913140-B2 Phosphonated PBI fiber PBI Performance Products (US) 2024-02-27 US disclosed
EP-3004213-B1 METHOD OF MAKING POLYBENZIMIDAZOLE PBI PERFORMANCE PRODUCTS INC (US) 2023-12-06 EP disclosed
US-7696298-B2 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2010-04-13 US disclosed
US-7696298-B2 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2010-04-13 US disclosed
US-20090131623-A1 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2009-05-21 US disclosed
US-20090131623-A1 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2009-05-21 US disclosed
US-20090131623-A1 Poly(arylenebenzimidazole) polymers and copolymers HAY ALLAN S 2009-05-21 US disclosed
EP-0511187-B1 Process for the preparation of 1H-benzimidazoles UCB SA (BE) 1996-11-20 EP disclosed
EP-0511187-A1 Process for the preparation of 1H-benzimidazoles U C B, S.A. (BE) 1992-10-28 EP disclosed
JP-S6291414-A PRODUCTION OF GRAPHITE FILM RES DEV CORP OF JAPAN 1987-04-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636618-B1 Asymmetric carbon molecular sieve hollow fiber membranes PHB2, PHB1, RICTOR NPC1 4114/4885RAB9A 4044/4885GAA 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.