Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027631 | 0.84 | TNKS (0.54) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL7945644 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1HPGDKMT2AGLA | |
| SCHEMBL7943519 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HPGDKMT2AGLA | |
| SCHEMBL12696294 | 0.79 | TNKS (0.52) | KDM4EALDH1A1HPGDCYP1A2TNKS | |
| SCHEMBL24021017 | 0.77 | CDK9 (0.54) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL30310501 | 0.77 | CDK9 (0.54) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL4740751 | 0.76 | GUSB (0.59) | KDM4EALDH1A1HPGDCYP1A2NPC1 | |
| SCHEMBL7941257 | 0.75 | KMT2A (0.54) | KDM4EALDH1A1HPGDKMT2AGLA | |
| SCHEMBL1664216 | 0.73 | KDM4E (0.97) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL16638382 | 0.73 | DHODH (0.70) | KDM4EALDH1A1HPGDKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087740-A1 | FLUORENONE 1, 4,-DIHYDROPYRIDIN DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005042495-A1 | (BENZIMIDAZOL-2-YL)-PHENYL-PHENYL-UREA COMPOUNDS AND METHODS FOR INHIBITING HEPARANASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-1472229-A1 | 5-RING HETEROCYCLES USED AS ANTIVIRAL AGENTS | Bayer HealthCare AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003064394-A1 | 5-RING HETEROCYCLES USED AS ANTIVIRAL AGENTS | BAYER HEALTHCARE AG (DE) | 2003-08-07 | — | — | WO | disclosed |