Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045812 | 0.86 | KMT2A (0.42) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15669862 | 0.79 | PTGS2 (0.47) | PTGS2CYP11B1CYP11B2SCN9AL3MBTL1 | |
| SCHEMBL15670125 | 0.78 | CNR1 (0.48) | PTGS2ALDH1A1KDRL3MBTL1CNR1 | |
| SCHEMBL15670295 | 0.77 | L3MBTL1 (0.52) | PTGS2MAPTMEN1KMT2ALMNA | |
| SCHEMBL27913679 | 0.76 | PTGS2 (0.37) | PTGS2MAPTCASP1PDK2MEN1 | |
| SCHEMBL27931866 | 0.76 | CYP11B1 (0.39) | PTGS2MAPTCASP1PDK2MEN1 | |
| SCHEMBL27913649 | 0.76 | CYP11B1 (0.39) | PTGS2MAPTCASP1PDK2MEN1 | |
| SCHEMBL16838822 | 0.76 | PTGS2 (0.38) | PTGS2MAPTCASP1PDK2MEN1 | |
| SCHEMBL19430888 | 0.75 | LMNA (0.41) | PTGS2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27913675 | 0.74 | PTGS2 (0.39) | PTGS2MAPTPDK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812755-A | Pyrazolopyridine derivatives as TTX-S blockers | RAQUALIA PHARMA INC | 2015-07-29 | — | — | CN | disclosed |