Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027391 | 0.84 | MAOA (0.31) | MAOALMNASLC6A2 | |
| SCHEMBL28027996 | 0.76 | ALDH1A1 (0.35) | ALDH1A1MAPTMAOA | |
| SCHEMBL3601616 | 0.73 | MAOA (0.44) | ALDH1A1MAPTMAOA | |
| SCHEMBL14367885 | 0.72 | HRH3 (0.44) | — | |
| SCHEMBL8251627 | 0.72 | HRH3 (0.44) | — | |
| SCHEMBL9825767 | 0.70 | SIRT2 (0.32) | MAOAUGT2B17 | |
| SCHEMBL2643783 | 0.69 | ELAVL3 (0.41) | ALDH1A1MAPT | |
| SCHEMBL14449468 | 0.68 | UGT2B17 (0.38) | ALDH1A1MAPTMAOAUGT2B17 | |
| SCHEMBL8259857 | 0.68 | HRH3 (0.37) | ALDH1A1MAOA | |
| SCHEMBL8259889 | 0.68 | CA2 (0.56) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |