SCHEMBL28028476

SCHEMBL28028476

CC(C)Cc1cnc(Br)s1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394759 0.78 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL10183130 0.78 SLC6A3 (0.42) FBP1ALDH1A1HPGD
SCHEMBL12648598 0.78 KMT2A (0.44) ALDH1A1
SCHEMBL5835893 0.77 ALDH1A1 (0.46) FBP1ALDH1A1HPGDEPHX2
SCHEMBL1913019 0.77 ALDH1A1 (0.30) ALDH1A1HPGD
SCHEMBL1913016 0.77 ALDH1A1 (0.30) ALDH1A1HPGD
SCHEMBL20341001 0.75 FBP1 (0.34) FBP1
SCHEMBL15055229 0.75 CA2 (0.40) ALDH1A1
SCHEMBL3072164 0.75
SCHEMBL21533859 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102199133-B 2 ', 2-double thiazole non-nucleosides compound and preparation method thereof, pharmaceutical composition and the purposes as hepatitis virus inhibitor SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2015-08-19 CN disclosed