Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388403 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2MCL1HSD11B1BRD4 | |
| SCHEMBL19336432 | 0.79 | GSTA1 (0.43) | ACMSDHNF4ADHFRMCL1IKBKB | |
| SCHEMBL29982561 | 0.76 | CYP3A4 (0.42) | MAPTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL24220 | 0.76 | CYP3A4 (0.42) | MAPTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL7673881 | 0.75 | ACMSD (0.61) | MAPTSMN1; SMN2ACMSDHNF4ADHFR | |
| SCHEMBL2070297 | 0.75 | MCL1 (0.72) | MAPTSMN1; SMN2ACMSDHNF4ADHFR | |
| SCHEMBL31413664 | 0.75 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2ACMSDHNF4ADHFR | |
| SCHEMBL7125464 | 0.75 | MAPT (0.53) | MAPTSMN1; SMN2ACMSDHNF4ADHFR | |
| SCHEMBL5951431 | 0.75 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2ACMSDHNF4ADHFR | |
| Ethane SCHEMBL28057225 | 0.74 | TRIM58 (0.45) | MAPTDHFRPTGS2KDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812790-B | Organopolysiloxane graft polymers | 花王株式会社 | 2019-04-12 | — | — | CN | disclosed |
| CN-104812790-A | Organopolysiloxane graft polymer | KAO CORP | 2015-07-29 | — | — | CN | disclosed |