Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220 | 0.94 | CYP3A4 (0.42) | MAPTSMN1; SMN2CYP3A4ALDH1A1LMNA | |
| SCHEMBL29982561 | 0.94 | CYP3A4 (0.42) | MAPTSMN1; SMN2CYP3A4ALDH1A1LMNA | |
| Acrylic Acid SCHEMBL28533340 | 0.87 | AKT1 (0.39) | SMN1; SMN2CYP3A4ALDH1A1LMNAKDM4E | |
| SCHEMBL28028503 | 0.82 | MAPT (0.47) | MAPTSMN1; SMN2HSD11B1KDM4EBRD4 | |
| SCHEMBL4258990 | 0.80 | SLC6A3 (0.51) | MAPTSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL9831971 | 0.80 | TDP1 (0.36) | CYP3A4ALDH1A1LMNAKDM4ECA12 | |
| Acetone SCHEMBL15254621 | 0.78 | ALDH1A1 (0.50) | MAPTSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL6693580 | 0.77 | CES2 (0.44) | CYP3A4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL38132 | 0.77 | ALDH1A1 (0.44) | MAPTSMN1; SMN2CYP3A4ALDH1A1LMNA | |
| SCHEMBL8579455 | 0.77 | LMNA (0.41) | MAPTSMN1; SMN2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927253-B1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-9351920-B2 | Organopolysiloxane graft polymer | KAO CORPORATION (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORPORATION (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2927253-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | Kao Corporation (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | IDUA, PIGS, GMNN | MAPT 2726/4885SMN1; SMN2 270/4885CYP3A4 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.