Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13496891 | 0.86 | ALDH1A1 (0.61) | TSHRTP53ALDH1A1KMT2ASMN1; SMN2 | |
| Terephthalic Acid SCHEMBL20240893 | 0.83 | TSHR (0.63) | TSHRTP53SRD5A2ALDH1A1CA12 | |
| Terephthalic Acid SCHEMBL29181739 | 0.83 | TSHR (0.71) | TSHRTP53SRD5A2ALDH1A1CA12 | |
| Isophthalic Acid SCHEMBL589816 | 0.82 | KDM4E (0.49) | CA12CA6CA9CA1CA2 | |
| Benzoic Acid SCHEMBL27395012 | 0.82 | DAO (0.47) | TSHRSRD5A2ALDH1A1MEN1KMT2A | |
| Terephthalic Acid SCHEMBL17835406 | 0.81 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA12 | |
| Terephthalic Acid SCHEMBL6453701 | 0.81 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA12 | |
| Terephthalic Acid SCHEMBL20240890 | 0.81 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA12 | |
| Terephthalic Acid SCHEMBL337710 | 0.81 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA12 | |
| Terephthalic Acid SCHEMBL7046508 | 0.81 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290287-A | Depolymerization method for realizing oriented recovery of PET (polyethylene terephthalate) fibers | 中国科学院青岛生物能源与过程研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-104884590-A | Ultra-low SAPS lubricating oil for internal combustion engines | CHEVRON ORONITE CO | 2015-09-02 | — | — | CN | disclosed |