Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915038 | 0.94 | MTNR1A (0.62) | MTNR1APOLBAPLNRNPC1PKM | |
| SCHEMBL8708565 | 0.89 | MTNR1A (0.58) | MTNR1AAPLNRMEN1KMT2ACNR1 | |
| SCHEMBL10784792 | 0.87 | POLB (0.55) | POLBAPLNRNPC1PKMRAB9A | |
| SCHEMBL490637 | 0.85 | POLB (0.71) | POLBAPLNRNPC1PKMRAB9A | |
| SCHEMBL266527 | 0.85 | NPC1 (0.58) | MTNR1APOLBAPLNRNPC1PKM | |
| SCHEMBL2398226 | 0.84 | POLB (0.53) | POLBAPLNRNPC1PKMRAB9A | |
| SCHEMBL16172631 | 0.84 | ACHE (0.48) | MTNR1ANPC1RAB9AALDH1A1 | |
| SCHEMBL585472 | 0.84 | APLNR (0.56) | POLBAPLNRNPC1PKMRAB9A | |
| SCHEMBL30522046 | 0.83 | KMT2A (0.56) | APLNRMEN1KMT2ACA12CA1 | |
| SCHEMBL3456256 | 0.83 | KMT2A (0.56) | APLNRMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781256-A | 3,4-disubstituted oxazolidinone derivatives and their use as inhibitors of the calcium activated potassium channel | HOFFMANN LA ROCHE | 2015-07-15 | — | — | CN | disclosed |