Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980610 | 0.93 | TRPA1 (0.43) | CYP19A1LMNAHPGDCNR2TRPA1 | |
| SCHEMBL193835 | 0.85 | HTR2A (0.52) | LMNACYP2D6KDM4ETDP1HTR2A | |
| Hydrochloric Acid SCHEMBL6251948 | 0.83 | HTR2A (0.50) | LMNACYP3A4CYP2D6KDM4ETDP1 | |
| Ammonia Solution, Strong SCHEMBL28352255 | 0.83 | HTR2A (0.50) | LMNACYP2D6KDM4ETDP1HTR2A | |
| SCHEMBL6699187 | 0.83 | CYP19A1 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CCYP19A1 | |
| SCHEMBL21855514 | 0.79 | CYP19A1 (0.51) | CACNA1BCACNA1CCYP19A1LMNAHTT | |
| SCHEMBL17814899 | 0.79 | HTT (0.42) | CYP19A1LMNAHTTNPSR1ALDH1A1 | |
| SCHEMBL11359363 | 0.79 | CHRNB2 (0.61) | LMNAALDH1A1HPGDCYP3A4CYP2D6 | |
| SCHEMBL7430169 | 0.77 | CYP19A1 (0.44) | CACNA2D1CACNA1BCACNB1CACNA1CCYP19A1 | |
| SCHEMBL7019079 | 0.77 | CNR1 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781256-B | 3,4 pairs of substitution oxazolidinone derivatives and its purposes as the inhibitor of calcium-activated potassium channel | 霍夫曼-拉罗奇有限公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-104781256-A | 3,4-disubstituted oxazolidinone derivatives and their use as inhibitors of the calcium activated potassium channel | HOFFMANN LA ROCHE | 2015-07-15 | — | — | CN | disclosed |