Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193835 | 0.85 | HTR2A (0.52) | LMNATRPA1TSHRHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL6251948 | 0.83 | HTR2A (0.50) | LMNATRPA1TSHRHTR2AHRH1 | |
| Ammonia Solution, Strong SCHEMBL28352255 | 0.83 | HTR2A (0.50) | LMNATRPA1TSHRHTR2AHRH1 | |
| SCHEMBL27468204 | 0.83 | CNR1 (0.54) | CNR1CNR2LMNATRPA1CACNA2D1 | |
| SCHEMBL10042121 | 0.82 | ALDH1A1 (0.47) | CNR1CNR2LMNACACNA2D1CACNA1B | |
| Dimethylamine SCHEMBL10622831 | 0.81 | HTR2A (0.52) | LMNATRPA1CASRTSHRALOX12 | |
| SCHEMBL29723649 | 0.81 | CNR1 (0.56) | CNR1CNR2LMNACASRCYP19A1 | |
| SCHEMBL11359363 | 0.79 | CHRNB2 (0.61) | LMNATRPA1CASRKMT2AALDH1A1 | |
| Acetic Acid SCHEMBL28538311 | 0.79 | MTNR1A (0.52) | LMNATRPA1KMT2AHTR2AHRH1 | |
| SCHEMBL2356591 | 0.79 | HTR2A (0.48) | CNR1CNR2LMNACACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387254-B2 | Prodrugs and drug-macromolecule conjugates having controlled drug release rates | PROLYNX LLC (US) | 2016-07-12 | — | — | US | disclosed |
| US-20140296476-A1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC | 2014-10-02 | — | — | US | disclosed |
| US-8680315-B2 | Prodrugs and drug-macromolecule conjugates having controlled drug release rates | PROLYNX, LLC (US) | 2014-03-25 | — | — | US | disclosed |
| EP-0901491-B1 | TROPANE DERIVATIVES USEABLE IN PARTICULAR FOR IN VIVO DETECTION OF DOPAMINE TRANSPORTERS | SCHERING AG (DE) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296476-A1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | ABCB1, ABCB11, DNPEP | CNR1 584/4885CNR2 1310/4885LMNA 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.