Methacrylic Acid

Methacrylic Acid

SCHEMBL28029464

C=C(C)C(=O)O.CNCCCC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.44
KDM4A O75164 1/20 0.43
KDM4C Q9H3R0 1/20 0.43
LMNA P02545 2/20 0.40
SLC22A6 Q4U2R8 2/20 0.40
TSHR P16473 5/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
AKR1B1 P15121 1/20 0.38
PRMT1 Q99873 1/20 0.38
PLA2G4A P47712 1/20 0.37
PPARG P37231 5/20 0.37
PPARD Q03181 5/20 0.37
PPARA Q07869 5/20 0.37
HDAC11 Q96DB2 4/20 0.37
GPR84 Q9NQS5 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288681 0.87
Hydrochloric Acid SCHEMBL380897 0.84
SCHEMBL9343010 0.84 LMNA (0.50) ADRA1AKDM4AKDM4CLMNASLC22A6
SCHEMBL580257 0.84
SCHEMBL27610031 0.84
Hydrogen Sulfide SCHEMBL28429267 0.82 KDM4A (0.48) ADRA1AKDM4AKDM4CLMNASLC22A6
Adipic Acid SCHEMBL5138045 0.82 LMNA (0.61) ADRA1ALMNASLC22A6TSHRNFKB1
Adipic Acid SCHEMBL27649164 0.82 LMNA (0.61) ADRA1ALMNASLC22A6TSHRNFKB1
Methacrylic Acid SCHEMBL28029782 0.80 ADRA1A (0.41) ADRA1ASLC22A6TSHRAKR1B1PLA2G4A
SCHEMBL693740 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870482-A Molecularly imprinted polymers and their use as antidandruff agents OREAL 2015-08-26 CN disclosed