Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967069 | 0.83 | ALDH1A1 (0.55) | MAPTRAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL2945883 | 0.80 | KMT2A (0.53) | MEN1KMT2AMAPTRAB9ATDP1 | |
| SCHEMBL2946374 | 0.80 | MEN1 (0.64) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL3096926 | 0.80 | NR1H4 (0.48) | MEN1KMT2ALMNAPOLBHPGD | |
| SCHEMBL11727915 | 0.80 | ALDH1A1 (0.63) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL2941803 | 0.79 | MAPT (0.56) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL2941168 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AMAPTRAB9ATDP1 | |
| SCHEMBL11417562 | 0.78 | MAPT (0.55) | MEN1KMT2AMAPTRAB9ATDP1 | |
| SCHEMBL1707504 | 0.77 | RAB9A (0.63) | MEN1KMT2AMAPTRAB9ATDP1 | |
| SCHEMBL4208672 | 0.77 | RAB9A (0.68) | MEN1KMT2AMAPTRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974059-B | A kind of Rivaroxaban intermediate and preparation method thereof | 北大方正集团有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104974105-A | Method of preparing 4-(4-aminophenyl)-3-morpholinone | UNIV PEKING FOUNDER GROUP CO | 2015-10-14 | — | — | CN | disclosed |
| CN-104974149-A | Preparation method of rivaroxaban | UNIV PEKING FOUNDER GROUP CO | 2015-10-14 | — | — | CN | disclosed |
| CN-104974148-A | Method of synthesizing 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidine-3-yl]phenyl}morpholine-3-one | UNIV PEKING FOUNDER GROUP CO | 2015-10-14 | — | — | CN | disclosed |
| CN-104974059-A | Rivaroxaban intermediate and preparation method thereof | UNIV PEKING FOUNDER GROUP CO | 2015-10-14 | — | — | CN | disclosed |