Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967069 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDKLK7LMNA | |
| SCHEMBL85867 | 0.82 | KLK7 (0.55) | POLBALDH1A1HPGDKLK7LMNA | |
| SCHEMBL28029676 | 0.80 | MEN1 (0.48) | KDM4EPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9250647 | 0.79 | ALDH1A1 (0.61) | NR1H4KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL5726377 | 0.79 | KMT2A (0.50) | NR1H4KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL2941168 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL9322346 | 0.78 | ALDH1A1 (0.59) | NR1H4KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL2945883 | 0.77 | KMT2A (0.53) | KDM4EPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL2946374 | 0.77 | MEN1 (0.64) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2941803 | 0.75 | MAPT (0.56) | POLBKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906516-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100256131-A1 | CARBONYL COMPOUNDS | TSAKLAKIDIS CHRISTOS | 2010-10-07 | — | — | US | disclosed |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | MERCK PATENT GMBH (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20060183739-A1 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256131-A1 | CARBONYL COMPOUNDS | F2, F11, PDHX | NR1H4 3304/4885KDM4E 1013/4885POLB 2957/4885 |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | F2, PDHX, SDHB | NR1H4 1718/4885KDM4E 1954/4885POLB 3094/4885 |
| US-20060183739-A1 | Carbonyl compounds | F2, F11, PDHX | NR1H4 3304/4885KDM4E 1013/4885POLB 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.