Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ME2 | P23368 | 1/20 | 0.42 |
| ▸ | ME1 | P48163 | 1/20 | 0.42 |
| ▸ | ME3 | Q16798 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910608 | 0.88 | MAPT (0.51) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL1955785 | 0.85 | PDK2 (0.51) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL28103092 | 0.84 | LTA4H (0.58) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL27906257 | 0.75 | LMNA (0.49) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL1955303 | 0.75 | PDK2 (0.51) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL5236570 | 0.75 | ALDH1A1 (0.64) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL1742180 | 0.73 | BCL2 (0.63) | — | |
| SCHEMBL1957162 | 0.73 | CYP2C9 (0.47) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL1955377 | 0.73 | LTA4H (0.53) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL18300991 | 0.72 | MAPT (0.52) | ALDH1A1TSHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947285-B | Sulfonamide derivatives as BCL-2-selective apoptosis inducers for the treatment of cancer and immune diseases | ABBVIE (US) | 2015-08-26 | — | — | CN | disclosed |