Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19596590 | 0.77 | CHRNB2 (0.37) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL28025502 | 0.77 | OPRM1 (0.43) | — | |
| SCHEMBL31371190 | 0.77 | CHRNB2 (0.37) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL27818815 | 0.75 | ACHE (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL28287292 | 0.74 | ALDH1A1 (0.40) | HPGDALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL28030156 | 0.74 | — | — | |
| SCHEMBL16245918 | 0.71 | CHRNB2 (0.41) | HPGDLMNATYRCHRNB2CHRNA4 | |
| SCHEMBL28699917 | 0.67 | TYR (0.36) | HPGDLMNAALDH1A1MAPTTYR | |
| SCHEMBL31371018 | 0.66 | CHRNB2 (0.36) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL16939755 | 0.65 | OPRM1 (0.32) | CHRNB2CHRNA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563438-A | Organic compounds | 奇华顿股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-104918948-B | Catalyst | 博里利斯股份公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-104918948-A | Catalyst | BOREALIS AG | 2015-09-16 | — | — | CN | disclosed |